The debates and conflicting results extended to previous studies regarding the role of MBL polymorphism in the susceptibility to infection, sepsis, septic shock and sepsis outcome, Gordon et al. found significant a relationship between exon 1 polymorphisms and between developing sepsis in adult an population in England [46]; Liu et al. also found a significant association between codon 54 polymorphism and the risk of sepsis in an adult Han Chinese population [8]. This evidence concerns the gene MBL2 and infection.