Cluster analysis of both cancer tissues and cancer cell lines also highlighted upregulations in genes related to the JAK/STAT signaling pathway, the mechanistic target of rapamycin (mTOR) signaling pathway (downstream of JAK/STAT), and genes related to the PRC2 polycomb complex, which are involved in epigenetic modification (H3K27 trimethylation). This evidence concerns the gene MTOR and cancer.