APOB and coronary atherosclerosis: As we expected, the potential value of radiomics in predicting intermediate-high SS (AUC, 0.741; 95% CI: 0.646–0.835) in combination with clinical features (HDL and Apo B) and 3D-US features of carotid plaques (plaque volume) enriched the study of the association of carotid plaque with coronary atherosclerosis and provided a noninvasive method to assess coronary artery severity before coronary angiography.