ABCC3 and breast carcinoma: In this line, Wang et al. have demonstrated that the antioxidant tetramethylpyrazine reduces the expression of ABCC3 [78]; moreover, Zeng et al. have shown that the combination of curcumol with doxorubicin increases the sensitivity of tumors to anticancer treatment by decreasing the expression of ABCC3 in breast cancer [79].