To delineate the role of LPA3 and its underlying mechanism in regulating mitochondrial activity, we subjected the siRNA control and LPA3 siRNA-treated human cervical cancer HeLa cells to a cell proliferation assay with electron transport chain (ETC) complex I inhibitor, Rotenone, and complex III inhibitor, Antimycin A (Figure 1A). Here, LPAR3 is linked to cervical carcinoma.