By analysing serum titres of thyroid peroxidase and thyroglobulin antibodies, as well as circulating levels of thyrotropin, free thyroid hormones, and 25-hydroxyvitamin D the authors concluded that the effect of exogenous vitamin D supplementation on thyroid autoimmunity was more pronounced in the supplemented group than in the native one, indicating possible benefits in a combined treatment of selenium and vitamin D for Hashimoto’s thyroiditis [165]. This evidence concerns the gene TG and autoimmune thyroid disease.