Baicalin is the main component found in Scutellaria baicalensis root, an herb widely used in traditional Chinese medicine, which can alleviate hyperglycemia-induced endothelial impairment by downregulating ROS and inflammation via the AKT1/GSK3B/FYN-mediated NRF2 activation [108]. Here, NFE2L2 is linked to Hyperglycemia.