The anti-cancer and anti-inflammatory effects of UA are mediated via various signaling cascades, including the signal transducer and activator of transcription 3 (STAT3) and NF-κB signaling pathways [95] and the Akt/p70S6K signaling pathways [96] to suppress tumor growth, survival and metastases [93]. Here, NFKB1 is linked to cancer.