POMC and infantile spasms: The aim of the study was to assess the short-term efficacy (during treatment schedule) and long-term outcome of intramuscular 0.02 mg/kg/day ACTH (tetracosactide) depot, used concomitantly with other antiepileptic drugs in patients with infantile spasms who did not achieve seizure cessation or relapse when taking only the AEDs.