Cytokine storm is an acute systemic inflammatory syndrome that occurs when there is an overwhelming increase in proinflammatory circulatory cytokine levels, such as those observed in certain cases of COVID-19, (Interleukin (IL)-1β, -2, -4, -6, -7, -8, -9, -10, -18, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon γ-induced protein (IP)-10, monocyte chemoattractant protein-1 and -3, macrophage inflammatory protein 1α, cutaneous T cell-attracting chemokine, interferon-γ (IFN-γ), and tumor necrosis factor-α) [148,149,150,151,152]. Here, CSF2 is linked to COVID-19.