MiR-205 has been found to bind to the 3′ UTR of LRRK2 and downregulate its expression, while brain samples from the frontal cortex of PD patients displayed increased levels of the LRRK2 protein and low levels of miR-205, supporting its crucial role in LRRK2 gene suppression [35]. The gene discussed is LRRK2; the disease is Parkinson disease.