PPIG and Parkinson disease: In regard to potential treatment approaches related to DNA methylation in PD, it has recently been demonstrated that the use of β-naphthoflavone and ethanol, two CYP inducers, in MPP+-treated cells was associated with increased cell viability, lower levels of ROS, the rescue of mitochondrial membrane potential, and the protection of the activity of mitochondrial complex I against MPP+-induced effects [148].