Interestingly, in the sensitivity quadrant, scores from all PMD and SYNGAP1-ID patients in this study were “more” (9/41, 22% PMD; 5/24, 21% SYNGAP1-ID) or “much more” (32/41, 78% PMD; 19/24, 79% SYNGAP1-ID) than typically developing individuals (Figure 2C). Here, SYNGAP1 is linked to Pelizeaus-Merzbacher spectrum disorder.