INS and Hypoglycemia: It is not necessary that every surge in insulin shall be associated with hypoglycemia as there are other compensatory mechanisms, such as the secondary messenger system, i.e., secretion of glucagon, sympathomimetic activity (secretion of epinephrine), and a glycogenolysis-like effect, which were not the domain of our study at this stage and require further studies to identify the underlying mechanism in euglycemics (working pancreas).