CRP and heart failure: In contrast to previous studies that indicated that preoperative hsCRP circulating levels can be useful biomarkers for predicting the subsequent risk of MACEs in patients with myocardial infarction and 6-month post-operative cardiovascular events [22], observations in our study cohort identify CRP elevation in patients with primary ACS as a marker of heart failure but not of MACEs following PCI, suggesting that distinct mechanisms may be at play in these two outcomes.