However, the USP15 gene is deleted in 25.37% of pancreatic cancers and 10.9% of glioblastomas, implying a potential tumor suppressive function of USP15 in these cancers [69].USP15 is involved in various cellular processes, such as cell proliferation, cell invasion, apoptosis, autophagy, the cell cycle, genome integrity, transcription regulation, the immune response, and others. This evidence concerns the gene USP15 and pancreatic neoplasm.