In another study, O’Rourke et al. [38] used a low-density native antigen reverse capture microarray comprising monoclonal antibodies against 27 pre-selected TAAs to ultimately select five TAAs (PARK7, CALD1, TARDBP, TLN1, and PSIP1) capable of discriminating between the PSA level-matched groups of patients with PC and BPH with ROC AUC 0.95 compared with that of PSA 0.5 (i.e., complete lack of discriminative power). The gene discussed is KLK3; the disease is benign prostatic hyperplasia.