ERBB2 and glioblastoma: Zhang et al. (2016) [237] evaluated the effect of NK-92/5.28.z cells—which are ErbB2-specific CAR-NK cells—both in NSG immunodeficient mice bearing orthotopic human GBM xenografts, and in C57BL/6 immunocompetent mice with murine subcutaneous or orthotopic GBM cells expressing ErbB2.