In the angiotensin II and 3.4-benzopyrene model, they used daily doses of 20 mg/kg and 80 mg/kg for 6 weeks [42], while CAG, in the elastase wrapping model, was given in a low dose 62.5 mg/kg or high dose 125 mg/kg daily for 14 or 28 days perorally, starting at the day of experiment or at 14 days (high dose only) after AAA induction [19]. The gene discussed is AGT; the disease is triple-A syndrome.