BCR and diffuse large B-cell lymphoma: In another transcriptomic approach, a consensus cluster classification (CCC) identified three subgroups: the BCR/proliferation cluster (BCR-DLBCL) displaying up-regulation of genes encoding B-cell receptor (BCR) signaling components, the OxPhos cluster (OxPhos-DLBCL) significantly enriched in genes involved in mitochondrial oxidative phosphorylation (OxPhos), and the host response (HR) tumors characterized by a brisk host inflammatory infiltrate [14].