CD4 and COVID-19: When our COVID-19 cohort was divided according to hospitalization requirements into non-hospitalized patients (n = 54) compared with hospitalized (n = 92) ones (Figure 1), non-hospitalized patients showed a higher median of total lymphocyte counts: 1300 (900–1600) vs. 1000 (800–1497) cells/μL, p = 0.012), CD4+ T cells: 718 (500–1026) vs. 610 (378-812) cells/μL (p = 0.004) and CD8+ T cells: 382 (238-558) vs. 266 (171–397) cells/μL (p = 0.003, Figure 3A–C).