High PBK/TOPK expression exhibited worse OS or DFS in BLCA (OS HR = 1.5, p = 0.08; DFS HR = 1.9, p = 0.015) and LUAD (OS HR = 2.2, p < 0.001; DFS HR = 2.4, p < 0.001). This evidence concerns the gene PBK and bladder transitional cell carcinoma.