PROM1 and Familial prostate cancer: In particular, the expression of surface biomarkers CD44, prominin-1 (CD133), as well as Nestin, were frequently reviewed [19,20,21,22,23,24,25], next to the expression of aldehyde dehydrogenase 1 (ALDH1), which indicates chemoresistance and poor prognosis of e.g., prostate cancer patients [26].