The phenotypic effects of lipid-associated GWAS polymorphisms might not be limited only by atherogenic changes in the lipid metabolism, and might involve other biological processes and metabolic pathways that play a role in atherosclerosis such as hemostasis (F2, coagulation factor II and ST3GAL4, ST3 beta-galactoside alpha-2,3-sialyltransferase 4), immune response and inflammation (LILRA3, leukocyte immunoglobulin like receptor A3), carbohydrate metabolic process (PPP1R3B, protein phosphatase 1 regulatory subunit 3B), and apoptosis (SCARB1, Scavenger receptor class B member 1). Here, F2 is linked to atherosclerosis.