Moreover, we found that the genetic susceptibility to CAD is associated with complex interactions between 14 polymorphic genes including ABCA1, APOC1, CETP, F2, GALNT2, LPA, NPC1L1, PLTP, PSKH1, ST3GAL4, STARD3, ZNF648, SCARB1, and PPP1R3B. The gene discussed is LPA; the disease is coronary artery disorder.