Moreover, we found that the genetic susceptibility to CAD is associated with complex interactions between 14 polymorphic genes including ABCA1, APOC1, CETP, F2, GALNT2, LPA, NPC1L1, PLTP, PSKH1, ST3GAL4, STARD3, ZNF648, SCARB1, and PPP1R3B. This evidence concerns the gene ZNF648 and coronary artery disorder.