Allele of rs55730499-C that showed protective effect against CAD susceptibility was predicted to increase an affinity to binding to six TFs such as androgen receptor AR (UniProtKB-P10275), involved in transcriptional regulation of gene expression by suppressing androgen-induced signal transduction and cell proliferation, E2F2 (UniProtKB-Q14209) activating of genes involved into the cell cycle and DNA replication, and ETF3 (UniProtKB-O00716) also activating cell cycle and DNA replication genes as well as suppressing adipogenesis. Here, E2F2 is linked to coronary artery disorder.