PLTP and atherosclerosis: This assumption may be supported by the finding of pleiotropic effects of some lipid-associated GWAS loci (i.e., rs11220463 ST3GAL4, rs4420638 APOC1, rs9987289 PPP1R3B and rs6065906 PLTP) on the levels of plasma lipids (i.e., TC, LDL-C, HDL-C, and TG), as well as on the levels of C-reactive protein as an inflammation marker of atherosclerosis [64].