To the best of our knowledge, apart from nine genes (Atp6v0a1, Tmem106b, Bmpr2, Ups11, Fos, Junb, Acsl4, Tyro3, and Scd2), the overlapping of the remaining 49 genes with datasets of DEGs from neurodegenerative mouse models of ALS and AD, is here reported for the first time. This evidence concerns the gene SCD5 and amyotrophic lateral sclerosis.