To the best of our knowledge, apart from nine genes (Atp6v0a1, Tmem106b, Bmpr2, Ups11, Fos, Junb, Acsl4, Tyro3, and Scd2), the overlapping of the remaining 49 genes with datasets of DEGs from neurodegenerative mouse models of ALS and AD, is here reported for the first time. Here, SCD5 is linked to Alzheimer disease.