CEBPD and pancreatic neoplasm: At this moment, we do not have an explanation for the small additive effect of macrophage conditioned medium on 5-FU- and paclitaxel-induced cytotoxicity, but most importantly our data highlight that C/EBPδ specifically acts upon gemcitabine resistance of pancreatic cancer cells and that C/EBPδ is not a generic player in PDAC chemoresistance.