The treatment of mice bearing TNBC tumors with 5 mg/kg/day of Pd2Spm for five days (cumulative dose of 25 mg/kg) induced significant effects: (i) decrease in tumor volume to a similar extent to that observed in animals treated with 2 mg/kg/day of cisplatin (cumulative dose of 10 mg/kg); (ii) reduction in the number of mitoses in the tumor; (iii) decrease in the proliferative index measured with immunohistochemical marker Ki67; and (iv) increase in TUNEL-positive cells (in the tumor), which are indicative of increased DNA damage. This evidence concerns the gene MKI67 and neoplasm.