In a small, microarray-based study of 25 primary pediatric acute pre-B-cell leukemias (ALL), extremely high levels of MondoA expression were found in leukemic blasts relative to fetal pre-B cells and numerous normal tissues, including peripheral blood and bone marrow (p = 1.6 × 10−21) [96]. This evidence concerns the gene MLXIP and acute lymphoblastic leukemia.