The human MXD2 gene, located on chromosome 10q25.2 (https://omim.org/entry/600020, accessed on 3 July 2021), resides within a locus that is often subject to recurrent deletion and LOH in several human tumors, most notably over half of prostate cancers and glioblastomas [218,219,220,221,222,223,224,225,226,227,228,229,230,231]. The gene discussed is MXI1; the disease is Familial prostate cancer.