In addition to the above-discussed post-translational varieties of regulation, Mxd1 stability is also regulated at the post-transcriptional level by miR19a/b, which are products of the six-member miR-17-92 cluster that is both over-expressed by and drives numerous cancers, promotes epithelial-mesenchymal transition and is a direct Myc target [204,205,206,207,208,209,210,211,212,213,214]. This evidence concerns the gene MYC and cancer.