When the study subjects were stratified by CRMP2 staining score, frequency of higher CRMP2 expression was significantly lower in CRC-DM patients (Table 2, 2+: p = 0.002 with OR 0.027~0.426, and 3+: p < 0.0001 with OR 0.006~0.222). Here, DPYSL2 is linked to diabetes mellitus.