However, when healthy monocytes were cocultured with cancer patients’ NK cells, the cytotoxic function of NK cells was slightly suppressed when treated with IL-2 alone (Figure 2A and Figure S2A) and was increased when treated with IL-2 + anti-CD16 mAbs (Figure 2B and Figure S2B) or IL-2 + sAJ2 (Figure 2C and Figure S2C) when compared to that of patient NK cells in the absence of monocytes. This evidence concerns the gene IL2 and cancer.