ERBB2 and breast carcinoma: HER2/neu (Chr17q12-21) [62] and CCR7 (Figure 1) are located close together on chromosome 17 and CCR7 is co-amplified with HER2/neu in approximately 20% of cases [63], although approximately 4% of HER2 amplified breast cancer samples were associated with CCR7 genomic deletion [63].