Although different markers were used to evaluate EMT in cancers, there was a consistent CCR7-induced increased activation of Slug, N-cadherin, TGF-β, vimentin, phospho-ERK, phospho-Akt, MMP-2, MMP-9 and Snail attenuation of E-cadherin [75,76,87,104,119,142,148,199,209,245,269,284,303]. This evidence concerns the gene CDH2 and cancer.