Among these omega-3 fatty acids, being highly polyunsaturated, oxidize easily and stimulate PPAR-α, causing a decrease in lipid levels and the elimination of triglycerides from the plasma with a consequent increase in the levels of high-density lipoprotein cholesterol (HDL) and reduction of inflammation and arteriosclerosis in the cardiovascular system. This evidence concerns the gene PPARA and arteriosclerosis.