Like the other members of the PPAR family, it mainly intervenes in the metabolism of lipids, participating in the oxidation of fatty acids, both at the level of adipose tissue, reducing adiposity, and consequently preventing the development of obesity, both at the level of skeletal muscles and heart and regulating the concentrations of cholesterol and blood glucose [32]. This evidence concerns the gene PPARA and obesity due to melanocortin 4 receptor deficiency.