Levels of serum interleukin (IL)-2, IL-6, IL-7, IL-10, tumor necrosis factor (TNF)-α, granulocyte-macrophage colony-stimulating factor (GM-CSF), interferon-inducible-protein-10, monocyte chemotactic protein-1, and macrophage-inflammatory-protein-1 alpha are significantly higher in severe COVID-19.9 This evidence concerns the gene TNF and COVID-19.