Intriguingly, we observed an increase in both glycosyltransferase and glycosidase enzymes in GBM versus controls, specifically, dolichyl-diphosphooligosaccharide-protein glycosyltransferase various subunit (STT3A, STT3B, 1, 2, 48 kDa). The gene discussed is STT3B; the disease is glioblastoma.