GANAB and glioblastoma: Notably, glycosidase enzymes including mannosyl-oligosaccharide glucosidase, glucosidase two subunit beta, and neutral alpha-glucosidase AB were elevated for GBM samples; specifically, PRO and MES subtypes compared to control samples (supplemental File S10), indicating an increase in maturation and processing of high mannose N-glycans to complex N-glycans in GBM.