However, none of the 10 proteins identified for amyotrophic lateral sclerosis in the meta-analysis were validated in the four MS proteomics studies performed since.134,144–146 Interestingly, TTR and nerve-growth factor ‘inducible’ have also been identified in a subsequent publication as potential biomarkers for frontotemporal dementia.133. Here, NGF is linked to amyotrophic lateral sclerosis.