This reflected the small number of patients examined with MRI in two dominant ataxias, i.e., SCA40 (OMIM 616053) and SCA45 (OMIM 617769), and two recessive ataxias, i.e., SCAR12 (OMIM 614322) and SCAR15 (OMIM 615705). The gene discussed is WWOX; the disease is cerebellar ataxia.