The distribution is characteristic in HLD2 (OMIM 608804) [53], (LBSL) (OMIM 611105) [55], leukoencephalopathy with ataxia (OMIM 615651) [56], (SANDO) (OMIM 607459) [57], SCAR4/SCA24 (OMIM 607317)[58] and X-linked fragile-X tremor ataxia syndrome (FXTAS) (OMIM 300623) [59]. The gene discussed is GJC2; the disease is Ataxia.