Previous work has shown that mutations in BBS-7, a conserved protein involved in trafficking of molecular cargos along the primary cilium of neurons, and linked to Bardet–Biedl syndrome (Liu and Lechtreck, 2018; Tan et al., 2007), lead to increased neurosecretion from ADL (Lee et al., 2011). This evidence concerns the gene BBS7 and Bardet-Biedl syndrome.