Precisely, some investigations indicated a strong association between CRP levels and ALFSRS‐R score, illness progression, and survival status in ALS patients, whereas others did not (Beers et al., 2020; De Schaepdryver et al., 2020; Huang et al., 2020; Keizman et al., 2009; Lunetta et al., 2017; Ryberg et al., 2010). This evidence concerns the gene CRP and amyotrophic lateral sclerosis.