Similarly, cumulative survival was reduced for UCEC patients, expressing CREG1 (HR = 1.32, p = 0.048), SIX1 (HR = 1.85, p = 0.0001), and MEOX1 (HR=1.43, p=0.0079) (Fig. 4A, B. These results suggest that the 38 TFs are associated with patient survival in a wide range of cancers, highlighting overlapping mechanisms, processes, and gene networks and indicating that these could be used as biomarkers for outcome for a range of cancers. The gene discussed is SIX1; the disease is cancer.