For instance, MES-specific PRRX1 (sufficient to convert ADRN to MES subtypes) [5, 6] was overexpressed in tumour samples compared to matched normal tissue of multiple cancers including low-grade glioma, GBM, DLBCL, STAD, PAAD, and THYM. Here, PRRX1 is linked to diffuse large B-cell lymphoma.