For instance, ELK4, CBFB, IFI16, PRRX1, AEBP1, and GATA3 expression was associated with an unfavourable outcome in renal cancer revealing the significance of these TFs (pink and blue colours represent unfavourable and favourable prognosis, respectively) [55] (Fig. 5A). The gene discussed is IFI16; the disease is renal carcinoma.