For instance, ELK4, CBFB, IFI16, PRRX1, AEBP1, and GATA3 expression was associated with an unfavourable outcome in renal cancer revealing the significance of these TFs (pink and blue colours represent unfavourable and favourable prognosis, respectively) [55] (Fig. 5A). This evidence concerns the gene AEBP1 and renal carcinoma.