Similarly, higher Spearman’s risk and reduced survival were observed for LGG, STAD, mesothelioma (MESO), pheochromocytoma and paraganglioma (PCPG), and thyroid carcinoma (THCA) patients expressing SIX1, collectively suggesting the prognostic value of SIX1 in these cancers. The gene discussed is SIX1; the disease is paraganglioma.