In contrary, FAM65A expression levels in tumor tissue of breast invasive carcinoma (BRCA), kidney renal papillary cell carcinoma (KIRP), lung adenocarcinoma (LUAD), lung squamous cell carcinoma (LUSC), uterine corpus endometrial carcinoma (UCEC), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), Glioblastoma multiforme (GBM), kidney renal clear cell carcinoma (KIRC) and Pancreatic adenocarcinoma (PAAD) are lower than the corresponding normal tissue based on TCGA dataset (Fig. 1a). The gene discussed is RIPOR1; the disease is squamous cell lung carcinoma.