R809C/H alteration, which was found in one case of PRAD, one case of UCEC and one case of SKCM, leads to a frame shift mutation of FAM65A, translation from R (Arginine) to C (Cysteine) or H (Histidine) at the 809 site of FAM65A protein and FAM65A protein was subsequently truncated. Here, RIPOR1 is linked to prostate adenocarcinoma.