Briefly, miR-124 is suppressed because the Gli2 combines with the upstream region of miR-124 transcriptional initiation locus excessively, whereas miR-124 existence is relevant to AURKA expression, giving rise to the anomaly of AURKA expression in glioma cells, which ultimately promotes cell proliferation and tumorigenesis [45, 46]. This evidence concerns the gene AURKA and central nervous system cancer.