A recent large prospective cohort study by Gao et al. [46] found that six predictors collected at the first antenatal care visit (advanced maternal age, elevated BMI, height, systolic blood pressure (SBP) and serum alanine transaminase (ALT), and family history of diabetes in first-degree relatives) and four during pregnancy modifiable risk factors (reduced physical activity, increased sitting time at home, passive smoking, and excessive weight gain), were associated with an increased risk of GDM in Chinese women (AUC of 0.712 (95% CI: 0.682 to 0.743)). The gene discussed is GPT; the disease is gestational diabetes.