Extracardiac phenotypic spectrum related to 6q25.1 deletion syndrome and TAB2 pathogenic variants is highly variable, including facial dysmorphisms, intrauterine growth restriction (IUGR), short stature, hypotonia, and connective tissue abnormalities such as joint laxity or hypermobility, developmental delay and possible ID [37]. This evidence concerns the gene TAB2 and fetal growth restriction.