TNF and colorectal carcinoma: The anti-inflammatory activity of C. lentillifera polysaccharides has been reported to have an inhibitory impact on lipopolysaccharide (LPS)-induced HT29 colorectal carcinoma cells, lowering the overproduction of TNF-α and IL-1β, SIgA and mucin2 (related proteins), as well as decreasing TNF-α and IL-1β expression [27].