Multivariate analysis showed that MDT intervention and radical surgery were protective factors that decreased the mortality of advanced GC (HR = 0.493, p < 0.001; HR = 0.127, p < 0.001), while stomach body carcinoma, poorly differentiated adenocarcinoma, N3 stage and elevated CEA were adverse factors that increases the mortality in advanced GC (Table 2). This evidence concerns the gene CEACAM5 and gastric cancer.