The models based on tumor number, microscopic vascular invasion, tumor differentiation, preoperative alpha-fetoprotein level, albumin–bilirubin grade, liver segment invasion, neutrophil-to-lymphocyte ratio or platelet-to-neutrophil ratio, and surgical margin or intraoperative blood transfusion for predicting the prognosis of HHCC with liver resection showed more accurate prognostic predictions [19]. This evidence concerns the gene AFP and neoplasm.