Thus, the conjugated 5-(4-isothiocyanatophenyl)-10,15,20-tri-(3,5-dihydroxyphenyl) porphyrin and 5-(4-isothiocyantophenyl)-10,15,20-tris-(4-Nmethylpyridiniumyl) porphyrin to murine mAbs 35A7 and FSP 77 via amine-isothiocyanate coupling mAb 35A7 recognizes carcinoembryonic antigen (CEA), which is overexpressed in colon adenocarcinomas, and mAb FSP 77 recognizes the extracellular domain of the erb-B2 receptor, which is overexpressed in ovarian and breast cancers. This evidence concerns the gene CEACAM5 and breast cancer.