The possibility that such correlation only relies on the side-effects of these substances is not conclusive, since these effects occur in a minority of cases and are occasionally described after the consumption of a variety of medicines (e.g., no relation with RTC was found for one of the medicines mostly used by patients with diabetes, insulin, the side-effects of which are consistent with those of medicines correlated with an augmented risk of RTC; [37]). Here, INS is linked to diabetes mellitus.