Sepsis is the most common cause of mortality among patients admitted to Intensive Care Unit (ICU).1,2 Recent evidence suggests the association of higher C-reactive protein (CRP)/Albumin value with sepsis.3,4 On admission CRP/Albumin has been reported to have high predictive capability of sepsis.5 Various researches suggest its role as an independent predictor of mortality among patient with sepsis in ICU.6,7. This evidence concerns the gene CRP and Sepsis.