AIM2 and cancer: cGAS/STING and AIM2/caspase 1 inflammasomes were activated by TTFields in luciferase-tagged KR158 cells (KR158-luc) and GL261 (GL261-luc) in a STING- and AIM2-dependent manner (Supplemental Figure 12), confirming that TTFields-induced activation of cytosolic DNA sensors and their cognate inflammasomes is conserved across cancer cell types and species.