AIM2 and glioblastoma: In all GBM lines except for L2, the rates of formation of micronuclei clusters that recruit cGAS and AIM2 consistently decreased by 5- to greater than 50-fold after TTFields in ribociclib-arrested compared with cycling cells, while ribociclib alone did not increase micronuclei clusters (Figure 1D and Supplemental Figures 2 and 3).