STAT3 and primary cutaneous T-cell non-Hodgkin lymphoma: T cell isolates from lesional CTCL skin biopsies showed increased signal transducer and activator of transcription 3 (STAT3) phosphorylation compared with nonlesional T cells, which is a characteristic of malignant CTCL T cell populations (Netchiporouk et al., 2014; Sommer et al., 2004).